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Abstract #1704

T1 Relaxation Times of 31P Metabolites in Human Liver at 7T

Marek Chmelik1, Ivica Just Kukurova2, 3, Stephan Gruber2, Martin Krk4, Michal Povazan, 25, Martin Tkacov, 25, Ladislav Valkovic2, Siegfried Trattnig2, Wolfgang Bogner2

1MR Centre of Excellence, Dept. Radiology , Medical University of Vienna, Vienna, Austria; 2MR Centre of Excellence, Dept. Radiology, Medical University of Vienna, Vienna, Austria; 3Department of NMR and MS, Institute of Analytical Chemistry, Slovak University of Technology, Bratislava, Austria; 4Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; 5Department of Nuclear Physics and Biophysics, Faculty of Mathematics, Physics and Informatics, Commenius University, Bratislava, Slovakia


The purpose of this study was to measure T1 relaxation times of hepatic 31P metabolites at 7T, which are necessary for further method optimizations and corrections during data quantifications. T1 values of eight hepatic 31P metabolite resonances could be determined in our study. No significant differences in T1 were observed for hepatic 31P metabolites at 7 T compared to lower field strength (i.e. 2T and 3T). This absence of any significant changes in T1 with increasing B0 is consistent with previous observations in rat liver, where nearly identical T1 relaxation times were reported for 4.7 T and 8.5 T. <