Caleb Robert Dulaney1, Juebin Huang2, Manohar Roda3, Alexander P. Auchus2, Judy Rose James3
1School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States; 2Department of Neurology, University of Mississippi Medical Center, Jackson, MS, United States; 3Department of Radiology, University of Mississippi Medical Center, Jackson, MS, United States
This study explores the ability of DTI to analyze the functional architecture of a normal thigh muscle and explore the changes in DTI parameters from within various muscle compartments. DTI parameters in normal thighs were quantified and significant measureable differences between muscles in different parts of the thigh have been reported. DTI could potentially be used to detect subtle changes in skeletal muscles in diseases such as inflammatory myopathies or muscular dystrophies. These novel imaging markers may shed light on early detection, differential diagnosis, and monitoring of skeletal muscle diseases.