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Abstract #1909

Maximal Entropy Tractography

Lawrence R. Frank1, David Meyer2

1Radiology, UCSD, San Diego, CA, United States; 2Mathematics, UCSD, La Jolla, CA, United States


We have developed a fiber tractography method that computes the maximum entropy trajectories between locations and depends upon the global structure of the diffusion tensor field. Computation of the pathways requires only solving a simple eigenvector problem for which efficient numerical routines exist, and a simple iterative computation. This method has potential significance for a wide range of applications, including studies of brain connectivity.