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Abstract #1992

DTI and DCE Perfusion MRI Metrics Discriminate Chronic Infective from Chronic Inflammatory Knee Arthritis

Rishi Awasthi1, Rakesh Kumar Gupta1, Deepak Tripathi2, Vikas Agarwal2, Vinita Agrawal3, Prativa Sahoo4, Ram KS Rathore4

1Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India; 2Immunology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India; 3Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India; 4Mathematics & Statistics, Indian Institute of Technology, Kanpur, Kanpur, Uttar Pradesh, India


This study was performed on 73 patients who had inflammation in knee joint with age ranging from 18-65 years. DTI and DCE-MRI were performed on a 3T MR scanner. On discriminant analysis, DCE derived BV and DTI derived FA values were found to be significant discriminators between tubercular and non-tubercular inflammation with canonical correlation of 0.851. We were able to correctly classify a total of 98.6% of original grouped cases into tubercular and non-tubercular knee arthritis with very narrow range of overlapping values.