Paulo Loureiro de Sousa1, 2, Alexandre Vignaud3, Jean-Paul Armspach1
1Universit de Strasbourg, CNRS, Laboratoire d'Imagerie et de Neurosciences Cognitives (LINC), Strasbourg, France; 2Institut de Myologie, Paris, France; 3Siemens Healthcare, Saint Denis, France
There is increasing interest in using quantitative magnetization transfer imaging (qMTI) for investigation of the myelin integrity. Because qMTI results obtained from pulsed saturation experiments rely on an accurate knowledge of the power and offset frequency of RF saturation, inhomogeneities of the transmit (B1+) and/or the static field (B0), such as those observed in high field NMR imaging (≥ 3T), will lead to systematic errors in qMTI indices. In this work we investigate the feasibility of fast and simultaneous assessment of B0 and B1+ using a dual-echo Bloch-Siegert sequence (DEBS). in vivo results of field mapping using DEBS are presented.