Moreno Pasin1, Marios C. Yiannakas1, Ahmed Toosy2, Claudia A M Wheeler-Kingshott1
1NMR Research Unit, Department of Neuroinflammation, UCL Institute of Neurology, University College London, London, England, United Kingdom; 2NMR Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, London, United Kingdom
In this study we assess the performance of the ZOnally-magnified Oblique Multislice EPI (ZOOM-EPI) sequence using a reduced field of view for targeted areas of fMRI activation. We compared motor fMRI activations on 5 healthy subjects obtained using ZOOM-EPI with ones obtained using conventional GE-EPI and SE-EPI sequences in terms of their spatial localisation. Moreover we report the dimensions of the activated regions in each subject for the three different sequences. For all subjects the ZOOM-EPI showed good anatomical correspondence with the overlapping activated areas from the more conventional GE-EPI and SE-EPI sequences and more localised activation.