Jeehye Seo1, Hui-jin Song1, Seong-Uk Jin1, Hee-Kyung Kim1, Jang Woo Park1, Moon Han1, Jong Su Baeck1, Ji-Young Kim2, Yongmin Chang1, 3
1Medical & Biological Engineering, Kyungpook National University, Daegu, Jung-gu, Korea, Republic of; 2School of Medicine, Kyungpook National University, Daegu, Jung-gu, Korea, Republic of; 3Molecular Medicine, Kyungpook National University, Daegu, Jung-gu, Korea, Republic of
Fibromyalgia (FM) is a medical disorder characterized by chronic widespread pain, a heightened and painful response to pressure. Currently, no investigation is available for identifying the power spectral density of low frequency BOLD fluctuations during resting-state functional magnetic resonance imaging (rs-fMRI) while recent study evaluated functional connectivity of low frequency fluctuation in FM patients. Using seed-based analysis of low frequency BOLD fluctuations in pain related networks, our results demonstrated (1) the medial and lateral pain networks of slow fluctuation BOLD signal during rs-fMRI and (2) the differences in the power spectral density within pain-related networks between FM patients and healthy controls.