Jess Agulla1, David Brea1, Mara Prez-Mato1, Miguel Blanco1, Jos Castillo1, Pedro Ramos-Cabrer1
1Clinical Neuriosciences Research Laboratory, Department of Neurology, University Clinical Hospital, University of Santiago de Compostela, Santiago de Compostela, Spain
In this work we study the therapeutic capability of a theranostic agent targeted against cells of the peri-infarct tissue in stroke. We treated ischemic animals with targeted theranostic molecules doped with citicoline. We compare the therapeutic effects of these molecules with those induced by free administered citicoline, citicoline encapsulated in non-targeted liposomes and the respective controls.