Chao-Chun Lin1, 2, Wu-Chung Shen1, Yung-Jen Ho1, Yu-Chien Lo1, Po-Pang Tsai1, Chia-Wei Lin1, Chiao-Ying Wu1, Hing-Chiu Chang2, 3, Hsiao-Wen Chung<s
1Radiology, China Medical University Hospital, Taichung, Taiwan; 2Graduate Institute of Biomedical Engineering and Bioinformatics, National Taiwan University, Taipei, Taiwan; 3Applied Science Laboratory, GE Healthcare, Taipei, Taiwan; 4Electrical Engineering, National Taiwan University, Taipei, Taiwan; 5Center for Neuropsychiatry and Graduate Institute of immunology, China Medical University Hospital, Taichung, Taiwan; 6Neurosurgery, China Medical University Beigang Hospital, Beigang, Taiwan
This study is to longitudinal follow up the perfusion change after intracranial stem cell implantation in chronic stroke patient. Our preliminary result shows temporally increase cerebral blood flow and volume which then decrease and are lower than the baselines in the long-term follow up. The perfusion change is earlier than the clinical neurologic symptoms improvement which began from the 3months after stem cell implantation.