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Abstract #3136

Brain Tissue and Microstructure Alternations in Children with Trichotillomania

Geon-Ho Jahng1, Jee A Lee2, Min-Ji Kim1, Hyug-Gi Kim1, So-Youn Shin1, Geon-Ho Bahn2, Sun Mi Kim1, Chang-Woo Ryu1, Dal-Mo Yang1, Dong Wook Sung3,

1Radiology, Kyung Hee University Hospital at Gangdong, Kyung Hee University, Seoul, Korea, Republic of; 2Psychiatry, Kyung Hee University Hospital, Kyung Hee University, Korea, Republic of; 3Radiology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Korea, Republic of


Trichotillomania (TTM) is a poorly understood disorder that is characterized by repetitive hair pulling. Very few neuroimaging studies have been conducted on patients with TTM. No study has investigated neural correlates, such as grey matter and diffusion alterations, in patients with TTM. The objective of this study, therefore, was to investigate specific brain tissue loss with structural MRI and microstructural changes with diffusion tensor MRI in children and adolescents with TTM. Pediatric subjects who met criteria for TTM (n = 9) and age-, sex-, handedness-, and intelligence quotient-matched healthy controls (HC) (n = 10) were recruited.