Saori Watanabe1, Tosiaki Miyati1, Risa Yorimitsu1, Hirohito Kan2, Syuya Fujihara3, Harumasa Kasai2, Nobuyuki Arai2, Masaki Hara2, Yuta Shibamoto2
1Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan; 2Department of Radiology, Nagoya City University Hospital, Nagoya, Japan; 3School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
Diffusion analysis with the apparent diffusion coefficient (ADC) enabled to obtain information of bone marrow composition. However, it is appropriate that the unit of water molecular displacement in the bone marrow is gmh than gmm2/sech of ADC. Therefore, we evaluated water molecular displacement in the vertebral bone marrow using q-space analysis to provide the detailed information on vertebral bone marrow. Correlation of displacement vs BMD was greater than that of ADC vs BMD. Water molecular displacement analysis with q-space makes it noninvasively possible to obtain more detailed information of changing bone marrow composition, and metabolism.