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Abstract #3394

Dogs Whole Brain Probabilistic Diffusion Tensor Imaging Tractography Normalization: A Solution for Brain Image Normalization Difficulty Problems

Witaya Sungkarat1, Jiraporn Laothamatas1, Boonlert Lumlertdacha2, Supaporn Wacharapluesadee3, Thiravat Hemachudha4

1Advanced Diagnostic Imaging and Image-Guided Minimal Invasive Therapy Center and Radiology Dept., Ramathibodi Hospital Faculty of Medicine, Mahidol University, Rajataewe, Bangkok, Thailand; 2Queen Saovabha Memorial Institute, Thai Red Cross Society, Bangkok, Thailand; 3WHO Collaborating Center for Research and Training on Viral Zoonoses, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; 4Department of Medicine and WHO Collaborating Center for Research and Training on Viral Zoonoses, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand


A new normalization technique using whole brain probabilistic DTI tractography maps is presented. This technique can address immense brain variability, even in dogs brains. Both FSL and SPM2 were used. The usefulness of the technique was demonstrated in conducting voxel-based group analyses of FA and MD maps of rabid and normal dogs.