Hedok Lee1, Zvi Jacob1, Haifang Li2, Ruth Reinsel1, Shaonan Zhang1, Helene Benveniste1
1Anesthesiology, State University of New York at Stony Brook, Stony Brook, NY, United States; 2Radiology, State University of New York at Stony Brook, Stony Brook, NY
There is little information about brain growth and metabolic changes in children less than 8 years of age. We employed computerized whole brain analysis to analyze age related morphometric changes, in addition to characterizing metabolic status using proton magnetic resonance spectroscopy (1HMRS) in children 2-7 years of age. We found structures belonging to the limbic system and motor control are prominent areas of structural growth during this period while metabolite concentrations appear to be relatively stable during the brain maturation.