Daniel Kim1, Alexis Harrison2, Wilson King3, Li Feng4, Elwin Bassett5, Christopher J. McGann2, Nassir F. Marrouche2, Ricardo Otazo6
1Radiology, University of Utah, Salt Lake City, UT, United States; 2Internal Medicine, University of Utah; 3Division of Pediatric Cardiology, University of Utah; 4Sackler Institute of Graduate Biomedical Sciences, New York University; 5Physics, University of Utah; 6Radiology, New York University
Breath-hold cine b-SSFP MRI is the gold standard for imaging myocardial function. The need for multiple breath-holds, however, increases the examination time and likelihood for patient exhaustion from repeated breath-holds. We sought to develop a single breath-hold 3D b-SSFP cine MRI pulse sequence with 12-fold acceleration using a standard coil array, by employing a combination of compressed sensing and parallel imaging that exploits joint sparsity among all coil datasets, and compare its performance against multi-slice 2D b-SSFP cine MRI for LV function quantification. All four global function measurements (EDV,ESV,SV,EF) were in good agreement, with coefficient of variation ranging from 6-12%.