Andreas Greiser1, Hui Xue2, Peter Schmitt1, Matthias Dieringer3, 4, Florian von Knobelsdorff-Brenkhoff3, 4, Thoralf Niendorf3, 4, Jeanette Schulz-Menger3
1Siemens AG, Healthcare Sector, Erlangen, Germany; 2Siemens Corporate Research, Princeton, NJ, United States; 3Berlin Ultrahigh Field Facility, Max-Delbrueck Center for Molecular Medicine, Berlin, Germany; 4Experimental and Clinical Research Center (ECRC), Charit Campus Buch, Humboldt-University, Berlin, Germany
T1 mapping is promising for quantifying myocardial integrity. We propose a new method to rapidly (in 5 sec) map T1 in the heart based on an IR-prepared real-time Cine TrueFISP sequence combined with an elaborate motion correction. The method was validated against the established MOLLI technique in T1 phantom measurements as well as in vivo (n=10) and one myocardial infarction patient. Phantom results showed good match between methods. in vivo at 3T TIRT overestimated T1 by 12.9% pre and 17.7% post contrast, but with M0 and improved motion correction the method may become a valid alternative for myocardial T1 quantification.