Andrew Nicholas Priest1, Ilse Joubert1, Teik Choon See1, Andrew Philip Winterbottom1, Martin John Graves1, David John Lomas1
1Department of Radiology, Addenbrookes Hospital and Cambridge University, Cambridge, United Kingdom
This study assesses the diagnostic performance of VANESSA, a new non-contrast-enhanced MRA technique, in patients with peripheral vascular disease, by comparison with our standard clinical contrast-enhanced protocol using TRICKS. The lower legs of 34 patients were imaged using both techniques, and two reviewers evaluated eight arterial segments for each dataset. The specificity and sensitivity for detection of significant disease (stenosis > 50%) were 75.6% and 91.4% when evaluated per segment, 89.7% and 72.7% when evaluated per limb and 97.6% and 44.4% when evaluated per patient. This method could be used to select patients for further investigation, reducing unnecessary Gadolinium administration.