Kristof Ralovich1, 2, Viorel Mihalef2, Puneet Sharma2, Lucian Itu3, Dime Vitanovski2, Razvan Ionasec2, Michael Suehling2, Allen Everett4, Giacomo Pongiglione
1Computer Aided Medical Procedures, TU Munich, Munich, Germany; 2Siemens Corporate Research, Princeton, NJ, United States; 3Universitatea Transilvania, Brasov, Romania; 4Johns Hopkins University; 5Ospedale Pediatrico Bambino Gesu, Rome, Italy
We present an integrated modeling and simulation framework for hemodynamic analysis of coarctation patients (post-stenting). 3D anatomical and 2D PC-MRI images are automatically processed to obtain the patient-specific anatomy and flow measurements, which are then used for performing patient-specific Computational Fluid Dynamics (CFD) simulations. A novel coupling of axi-symmetric 1D and 3D CFD unsteady simulations provides physiological boundary conditions for the overall simulation framework. As a first validation study, we compared the simulated and PC-MRI distal aortic flow rate in six patients. The promising initial results reiterate the potential of CFD simulations to provide assessment of post operative hemodynamics.