Kang Wang1, Ma. Daniela Cornejo2, Dan W. Rettmann3, James H. Holmes1, A. Muoz del Ro2, 4, Frank R. Korosec2, 4, Jean H. Brittain1, Scott K. Nagle2
1Global Applied Science Laboratory, GE Healthcare, Madison, WI, United States; 2Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; 3Global Applied Science Laboratory, GE Healthcare, Rochester, MN, United States; 4Radiology, University of Wisconsin-Madison, Madison, WI, United States
3D dynamic contrast enhanced (DCE) pulmonary perfusion imaging for simultaneous evaluation of vascular anatomy and a dynamic assessment of parenchymal microvascular enhancement has been a long sought after application and is finally becoming achievable due to recent advances in rapid imaging. However, it poses challenges for the required resolution in the spatial-temporal domain. In this work, we demonstrate the feasibility of using the DISCO (Differential Subsampling with Cartesian Ordering) technique for DCE pulmonary perfusion to achieve the necessary high spatial-temporal resolution for this application.