Krishna Juluru1, Jonathan P. Dyke1, Pascal Spincemaille1, Andrew H. Talal2, Rhonda Yantiss3
1Radiology, Weill Cornell Medical College, New York, NY, United States; 2Medicine, Weill Cornell Medical College, New York, NY, United States; 3Pathology, Weill Cornell Medical College, New York, NY, United States
The purpose of this study was to prospectively assess the feasibility of dynamic whole liver imaging using a spiral acquisition technique for the purpose of evaluation of liver fibrosis. The spiral technique allows whole liver imaging with high temporal resolution, while maintaining spatial resolution, and permitting sliding window reconstruction. Enhancement curves demonstrate differences in perfusion between subjects who are normal and who have biopsy-proven liver fibrosis.