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Abstract #4019

Accuracy of Gadoxetic Acid-Enhanced Magnetic Resonance Imaging for the Diagnosis of Sinusoidal Obstruction Syndrome in Patients with Chemotherapy-Treated Colorectal Liver Metastases

Na-Young Shin1, Myeong-Jin Kim1, Joon Seok Lim1, Mi-Suk Park1, Yong-Eun Chung1, Jin-Young Choi1, Ki Whang Kim1, Young-Nyun Park1

1Yonsei University Severance Hospital, Seoul, Korea, Republic of


To assess whether hepatobiliary phase images of gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) is a diagnostic finding of sinusoidal obstruction syndrome (SOS) in patients with hepatic metastases who have undergone chemotherapy, we retrospectively analysed EOB-MRI of 42 patients who had undergone chemotherapy before hepatic resection of colorectal hepatic metastases using a 5-point scale. Reticular hypointensity on hepatobiliary phase images of EOB-MRI is highly specific for the diagnosis of SOS in patients with treated colorectal hepatic metastases with good interobserver agreement.