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Abstract #4060

Feasibility of Regional Renal Blood Flow and Vascular Volume Fraction Measurement with Cardiac-Output Corrected MR Renography

Jeff L. Zhang1, 2, Henry Rusinek3, Christopher Conlin1, 2, Vivian S. Lee1

1Department of Radiology, University of Utah, Salt Lake City, UT, United States; 2Department of Bioengineering, University of Utah, Salt Lake City, UT, United States; 3Department of Radiology, New York University


In this study we performed a voxel-by-voxel analysis for the vascular phase of low-dose Gd-enhanced MR renography data and assessed the impact of cardiac output-corrected AIF on the precision of renal perfusion measurements. The estimated perfusion and vascular volume fraction agreed with literature value. The variability of perfusion was remarkably reduced with the use of CO-based AIF correction.