1Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; 2Radiology, University of Wisconsin-Madison, Madison, WI, United States
A least-squares based reconstruction is developed to simultaneously solve for both spatial and spectral encoding. By jointly solving both domains, spectral imaging can be performed with a spatially oversampled single-shot spiral acquisition. Simulations indicate that accurate single-shot imaging is possible with oversampling factors greater than six, even in situations of substantial T2* decay and ΔB0. With lower oversampling, two shots are required for similar accuracy. Simulations were confirmed with in-vivo experiments, showing accurate single-shot spectral imaging with an oversampling factor of 7. The proposed approach increases scan efficiency by reducing RF requirements, allowing accelerated acquisition speed and improved temporal/spatial resolution.