1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 2Siemens AG,Healthcare Sector, Erlangen, Germany; 3Department of Radiology, Case Western Reserve University, Cleveland, OH, United States; 4Case School of Engineering, Case Western Reserve University, Cleveland, OH, United States
MR Fingerprinting is a novel imaging concept to generate multiple parametric maps simultaneously by matching spatially and temporally incoherent signals to a pre-calculated dictionary. Here we explore MR fingerprinting using a QUick Echo Split Technique (QUEST) with a spiral trajectory to simultaneously generate T1, T2 and M0 maps. QUEST MRF achieves unique signal evolution by acquiring the maximum possible number of echoes for a small number of RF pulses. The results show that this method can be used to generate accurate quantitative maps and demonstrates the potential of MRF to explore unlimited pulse sequence designs.