Jeffrey MC Lau1, Richard Laforest2, Shivak Sharma1, Jonathan McConathy2, Agus Priatna2, 3, Luciano Amado1, Robert J. Gropler2, Pamela K. Woodard2
1Cardiology, Washington University in St. Louis, Saint Louis, MO, United States; 2Radiology, Washington University in St. Louis, Saint Louis, MO, United States; 3Siemens Medical Solutions, Malvern, PA, United States
The objective of this study is to determine the reproducibility of myocardial specific uptake values (SUVs) obtained in EKG-gated and non-EKG-gated cardiac 18F-FDG PET imaging using an MR attenuation correction (AC) &[mu] -map instead of CT. In non-EKG-gated PET-CT and PET-MR, there is excellent per patient correlation between the SUVs (R2 =0.97). In EKG-gated PET-MR, SUVs vary over the cardiac cycle, with higher SUV at end-systole and lower SUV at end-systole. Our findings show that, despite the marked differences in AC methods, myocardial PET SUVs measured using MR-AC show excellent correlation to myocardial SUVs obtained by standard PET-CT imaging.