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Abstract #0594

Clinical Utility of Endovaginal MRI at 3T with a Zonal Oblique Multislice (Zoom) Diffusion-Weighted Technique for Selecting Patients with Carcinoma of the Cervix for Fertility Sparing Surgery

K Downey1, M. Jafar1, S Hazell2, A D. Attygalle2, Veronica A. Morgan1, M Schmidt1, T. E. Ind3, D. P. Barton3, J. H. Shepherd3, Nandita M. deSouza1

1Magnetic Resonance Imaging, Institute of Cancer Research, Surrey, United Kingdom; 2Histopathology, The Royal Marsden Hospital, London, United Kingdom; 3Gynecological Surgery, The Royal Marsden Hospital, London, United Kingdom


Presentation of cervix carcinoma is often with small volume disease offering potential for fertility-sparing trachelectomy. Accurate preoperative depiction of tumor margins is crucial. The use of an endovaginal receiver coil has previously shown improvement in the detection of small tumors. At 3T EPI-DWI suffers disabling artefact and distortion with endovaginal coils. An alternative is Zoom-EPI (reduces distortion and improves resolution by reducing FOV). Purpose of study: Determine the sensitivity/specificity of T2-W + Zoom-DW imaging using an endovaginal coil at 3T for detecting cervical cancer, compare tumor:stromal contrast (T2-W vs. DWI) and document impact of the technique on surgical management.