1Radiology, Boston Children's Hospital, Boston, MA, United States; 2Radiology, A.A. Martinos Center for Biomedical Imaging/Massachusetts General Hospital, Charlestown, MA, United States; 3Newborn Medicine, Boston Children's Hospital, Boston, MA, United States; 4Newborn Medicine, Radiology, Boston Children's Hospital, Boston, MA, United States
The importance of the thalamus on motor, somatosensory and cognitive functions is well recognized. The study of the thalamic structure with its nuclear subdivisions in the pediatric population could shed a light on thalamic development and changes secondary to pathological states. In this study, we demonstrate the feasibility of thalamic parcellation in clusters that have an anatomical and functional correspondence to known thalamic nuclei in a neonatal population. This parcellation is derived from thalamic connections to predefined neocortical targets observed using probabilistic diffusion tractography.