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Abstract #0844

Baseline GABA Concentration More Strongly Predicts Baseline BOLD Signal Synchrony Than CBF in Visual Cortex

Swati Rane1, Emily Mason2, Subechhya Pradhan1, Erin Hussey2, Kevin Waddell1, John C. Gore1, 3, Brandon Ally, 24, Manus J. Donahue1, 4

1VUIIS, Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States; 2Neurology, Vanderbilt University, Nashville, TN, United States; 3Biomedical Engineering, Vanderbilt University, Nashville, TN, United States; 4Psychiatry, Vanderbilt University, Nashville, TN, United States


This study investigates the relationship between baseline BOLD synchrony and perfusion (CBF) and baseline GABA concentration in the visual cortex. BOLD synchrony at rest was more strongly correlated with baseline GABA levels than with absolute CBF.