Huilin Zhao1, Jinnan Wang2, 3, Xihai Zhao4, Xiaosheng Liu1, Ye Cao1, Jianrong Xu1, Daniel S. Hippe3, Chun Yuan3
1Radiology, Renji hospital, Shanghai Jiao Tong Univesity School of Medicine, Shanghai, China; 2Philips Research North America, Seattle, WA, United States; 3Radiology, University of Washington, Seattle, WA, United States; 4Center for Biomedical Imaging Research,Tsinghua University School of Medicine, Beijing, China
It has been shown that fast 3D black-blood (BB) MR sequence is capable of delineating both luminal and outer wall boundaries of bilateral carotid arteries. This study sought to determine the accuracy of this technique at quantifying carotid atherosclerotic disease compared to DSA in patients with at least 50% luminal stenosis. Our key findings are that very good agreement was found between 3D BB-MRI and DSA in assessing carotid luminal stenosis and ulceration. However, carotid stenotic lesion length measurements by 3D BB-MRI were significantly longer than that measured by DSA. These findings indicate that 3D BB-MRI has the potential to become an alternative imaging approach in evaluating the severity of carotid atherosclerotic disease.