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Abstract #0991

Using ASL MRI to Measure Perfusion and Arrival Time in Patients with Frontotemporal Lobar Degeneration

Helen Beaumont1, Geoff J. M. Parker1, Roland Zahn2, Laura M. Parkes1

1Centre for Imaging Sciences & Biomedical Imaging Institute, University of Manchester, Manchester, GMC, United Kingdom; 2Divisions of Psychology & Psychiatry, University of Manchester, Manchester, GMC, United Kingdom


Perfusion was greater in right occipital regions and cerebellum in patients compared to controls and was lower in right frontal and temporal regions. Arrival time showed more bilateral differences, being longer in insular, occipital and medial temporal regions in patients compared to controls and shorter in the caudate, amygdala and temporal regions.