M. Ayaz Khan1, 2, Jie Liu1, 2, Peiying Liu3, David Zhu4, Hanzhang Lu3, Rong Zhang1, 2
1Cardiology, University of Texas Southwestern Medical Center, Dallas, TX, United States; 2Institute for Exercise and Environmental Medicine, Dallas, TX, United States; 3Advance Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States; 4Cognitive Imaging Research Center, Michigan State University, East Lancing, MI, United States
Quantitative blood flow measurement is essential for assessment of cerebrovascular function under normal and diseased conditions. Color-coded duplex ultrasonography (CDUS) and phase contrast (PC) magnetic resonance imaging (MRI) are two commonly used non-invasive techniques for measuring CBF. However, previous studies showed substantial differences between these two methods. Recent development in ultrasoud technology and quantification of blood vessel diameter using the edge-detection and wall-tracking method have significantly improved the accuracty of CBF measurement using CDUS. In the present study, we compared CBF meauserments using the PC MRI with the high-resolution 2-D CDUS methods.