Andrew N. Priest1, Ilse Joubert1, Sarah Hilborne1, Sally Hunter1, David J. Bowden1, Martin John Graves1, Trevor Baglin2, Jonathan H. Gillard3, David J. Lomas1
1Department of Radiology, Addenbrookes Hospital and University of Cambridge, Cambridge, United Kingdom; 2Department of Haematology, Addenbrookes Hospital, Cambridge, United Kingdom; 3Department of Radiology, University of Cambridge, Cambridge, United Kingdom
MR Direct Thrombus Imaging (MR-DTI) is able to highlight acute thrombus, due to the short T1 relaxation time of met-haemoglobin. In this study, simulations and phantom measurements are used to optimise the SNR from thrombus while suppressing the blood signal. Fat suppression is particularly important for MR-DTI due to the short T1 of fat. This study also investigates the combination of MR-DTI with dual-echo Dixon imaging, allowing improved fat suppression, and thus improved depiction of thrombus, near the edge of the field of view. These methods are demonstrated in patients with acute deep vein thrombosis and carotid intraplaque haemorrhage.