Ye Tao1, Tina Ehtiati2, Jesse Klostranec3, Guan Wang1, AbdEl-Monem M. El-Sharkawy4, Monica S. Pearl1, William A. Edelstein1, Martin G. Radvany1
1Johns Hopkins School of Medicine, Baltimore, MD, United States; 2SiemensCorporate Research, Princeton, NJ, United States; 3University of Toronto School of Medicine, Toronto, Ontario, Canada; 4Johns Hopkins University, Baltimore, MD, United States
Various medical conditions require biopsy confirmation or minimally invasive image-guided interventions. MRI provides excellent visualization of anatomy and disease without ionizing radiation, but MRI interventional access is difficult and MRI compatible clinical equipment limited. CT has few equipment restrictions, but radiation exposure can be significant. Fusion/overlay of MRI and fluoroscopy suite cone-beam CT (CBCT) potentially combine the diagnostic quality of 3D MRI/CT imaging with the ease and speed of fluoroscopy and decreased radiation. We have developed a multimodality phantom containing simulated lesions occult to fluoroscopy, and have used MRI/CBCT image fusion guidance for successful simulated lesion biopsies.