Yuqing Huang1,
Zhiyong Zhang1, Shuhui Cai1, Zhong Chen1
1Department
of Electronic Science, Xiamen University, Xiamen, Fujian, China
Localized 2D J-resolved spectroscopy can separate chemical shifts and J couplings into two different dimensions. It is widely used for the detection of metabolites in biological tissues, even in in vivo study. However, due to the intrinsic magnetic susceptibility in biological tissues, the localized 2D J-resolved spectrum is usually suffered from field inhomogeneity. In this report, a new pulse sequence based on intermolecular single-quantum coherences is presented to obtain localized 2D J-resolved spectrum in inhomogeneous fields, which is potentially useful for studying biological metabolites.