Yu-Chun Lo1, Yu-Jen Chen1, Yung-Chin Hsu1, Wen-Yih Isaac Tseng1, 2
1Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, Taiwan; 2Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
In this study, a standard procedure of tractography was used to develop an atlas of fiber tracts of the whole brain. This procedure entailed a diffusion spectrum imaging (DSI) template on which interested fiber pathways and their ROIs were determined and validated by experts. A total of 107 major white matter tracts were reconstructed. Based on this atlas, a template-based approach was proposed to enable an automated analysis of the microstructural integrity of the tracts identified in the atlas. The atlas and the automated tract analysis method may facilitate the connectome study in a large cohort.