Mitsunobu Kunimi1, Sachiko Kiyama2, Toshiharu Nakai2
1National Center for Geriatrics and Gerontology, Obu, Aichi , Japan; 2National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
We attempted to evaluate the validity of divalent Task Switching Paradigm (TSP) as a cognitive stress test. Fifteen young and 15 elderly volunteers participated. The brain areas with augmented brain activation depending on the difficulty of TSP task were different between the two age groups. In particular, it was observed that the contrast of Elderly against Young of right caudate nucleus and hit rate score was significantly correlated with the activation in the right caudate nucleus in the Elderly. Evaluation of the activation in the caudate nucleus using TSP may be valid to represent the aging effects on reconfiguration function.