Elijah George1, 2, Steven Roys1, 3, Jiachen Zhuo1, Chandler Sours4, Rao P. Gullapalli1
1Magnetic Resonance Research Center, University of Maryland School of Medicine, Baltimore, MD, United States; 2Bioengineering, University of Maryland, College Park, MD, United States; 3Diagnostic Radiology & Nuclear Medicne, University of Maryland, Baltimore, MD, United States; 4Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD, United States
In Magnetic Resonance Spectroscopy studies of the human brain, the echo time (TE) of acquisition plays a huge role in determining which metabolite signals are present in the spectrum in addition to how well the baseline for signal quantification can be defined. Given that the scan times are long for MRSI, seldom both the long and short TE data is obtained on the same subject within the same session. Herein we describe a dual-echo (DE) MRSI acquisition that is capable of simultaneously acquiring both long and short TE data sets with the same scan time as a standard MRSI method and apply it on traumatic brain injury patients where the short and long T2 metabolites provide invaluable information.