Sheng Fang1, Wenchuan
Wu2, Kui Ying3, Hua Guo2
1Institute
of nulcear and new energy technology, Tsinghua University, Beijing, China; 2Center
for Biomedical Imaging Research,
Department of Biomedical Engineering,
School of Medicine, Tsinghua University, Beijing, China; 3Department
of engineering physics, Tsinghua University, Beijing, China
An ultra-fast variable density spiral (VDS) imaging technique using multiscale CORNOL (coherence regularization using a nonlocal operator) reconstruction is proposed. The multiscale CORNOL circumvents the conflict of large-scale artifact suppression and fine-scale structure perseveration of nonlinear reconstruction by sequentially handling these two tasks with smoothness constraint at different scales. This sequential procedure enables further reduction both residual aliasing artifact and ring-like artifact of VDS with well-preserved image details. Both simulation and in vivo experiment results demonstrate that the proposed method can suppress both large-scale artifacts and noise while preserving image details well at high sampling reduction factors.