Jing-Huei Lee1, Mathew Norris1, Elizabeth M. Fugate1, Nikolai I. Avdievich2, Hoby P. Hetherington2
1University of Cincinnati, Cincinnati, OH, United States; 2Yale University, New Haven, CT, United States
The development and implementation of the CMRO2 imaging approach based on high-field 17O magnetic resonance spectroscopic (MRS) imaging, combined with brief inhalation of 17O-isotope-enriched oxygen gas, has received increased interest. However, the low sensitivity of 17O MR signal has limited the potential of this technique. In this work, we introduced a novel double tuned 1H/17O head volume coil, in which the 1H coil is driven in quadrature mode and the 17O coil utilizes phased array approach.