T1rho in Acute Cerebral Infarctions

Toshiaki Akashi¹, Toshiaki Taoka¹, Saeka Hori¹, Tomoko Ochi¹, Toshiteru Miyasaka¹, Masahiko Sakamoto¹, Megumi Takewa², Tomoyuki Okuaki³, Kimihiko Kichikawa¹

We evaluated T1rho of acute cerebral infarctions of human. Seven patients with 8 lesions were enrolled. T1rho MRI was acquired by 3.0T clinical scanner (spin lock pulse; 500 Hz for 1, 10, and 80ms). T1rho maps were compared with hyperintense areas on DWI (haDWI). Seven of all showed entirely prolonged T1rho. In 4 of 7 lesions, mild elevation of T1rho was found around haDWI. One cortical lesion showed variable T1rho values, and area with abnormal T1rho was much larger than the haDWI. These mismatches between T1rho map and DWI may indicate penumbra regions or other pathological processes.