Sangwoo Lee1, Jeong Min Lee2, Jeong Hee Yoon2, Hiroyuki Kabasawa3
1Global Applied Science Lab, GE Healhcare, Gangnam-gu, Seoul, Korea; 2Radiology, Seoul National University Hospital, Jongno-gu, Seoul, Korea; 3Global Applied Science Laboratory, GE Healhcare, Hino-shi, Tokyo, Japan
IVIM (IntraVoxel Incoherent Motion) has been widely used in various clinical applications including liver fibrosis staging and hepatic tumor characterization. However, in those studies, there has been no consideration of T1 and T2 relaxation differences between blood and tissue within the IVIM signal model. It was reported that perfusion fraction can be significantly affected by imaging TE due to such relaxation differences. In this work, we demonstrated the feasibility of simultaneous estimation of tissue T2 map within single IVIM data acquisition and compensation of perfusion fraction using the acquired T2 map.