Shuya Fujihara1, Tosiaki Miyati2, Saori Watanabe2, 3, Naoki Ohno2, Takashi Hamaguchi2, Masako Takanaga2, Takayuki Miyazaki4
1Division of Health Sciences, Graduate School of Medical Sciences , Kanazawa University, Kanazawa, Ishikawa, Japan; 2Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan; 3Department of Radiology, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan; 4School of Health Sciences, College of Medical Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan
To comprehend the clinical physiology of the skeletal muscle disease, direct assessment of the muscle blood flow is essential. However, muscle blood flow (MBF) is the low baseline flow, and which tends to be maintained even in disease states. Thus MBF measurement should test under stress . The objective of our study is to evaluate how much change in the MBF of each lower-leg muscle at the long axis before and after exercise using three-dimensional (3D) pulsed-continuous arterial spin labeling (pCASL) MRI.3D-pCASL makes it possible to obtain volume blood flow data of the lower-leg muscle and evaluate change in regional blood flow of the lower-leg muscle after exercise.