Ke Li1, 2,
Richard D. Dortch1, 2, Ha-Kyu Jeong1, 2,
Amanda K.W. Buck1, 2, Theodore F. Towse, 23,
Bruce M. Damon1, 2, Jane H. Park4
1Institute
of Imaging Science, Vanderbilt University, Nashville, TN, United States; 2Radiology
and Radiological Sciences, Vanderbilt University, Nashville, TN, United
States; 3Physical Medicine and Rehabilitation, Vanderbilt
University, Nashville, TN, United States; 4Molecular Physiology
and Biophysics, Vanderbilt University, Nashville, TN, United States
DT-MRI indices from the normal human thigh muscles have particular significance because of the proximal-to-distal presentation of many neuromuscular disorders, causing the thigh muscles to be an early site of pathology. In this work, DT-MRI has been performed in healthy thigh muscles at 3.0 T in order to investigate the normal values obtained by, and the repeatability of, this technique.