Jose G. Raya1, Eike Dettmann1, Ali-mohammad Golestani1, Kai Tobias Block2
1Radiology, New York University Langone Medical Center, New York, NY, United States; 2Radiology, NYU Langone Medical Center, New York, NY, United States
Diffusion tensor imaging (DTI) of articular cartilage has demonstrated high accuracy (90%) for the diagnosis of osteoarthritis (OA). In vivo DTI of articular cartilage has been performed at 7 T, which limits its clinical applicability. To perform DTI of articular cartilage at 3 T we developed a radial spin echo diffusion tensor imaging (RAISED) sequence. We optimize the RAISED sequence for articular cartilage. Phantom measurements were used to test the accuracy of the DTI parameters. In vivo validation on healthy and OA subjects demonstrated the feasibility of the RAISED sequence for in vivo DTI of articular cartilage at 3 T.