Abstract #3560

Neural Activation Associated with Inhibition Control in Working Memory Maintenance and Its Correlation with Brain Volume Changes in Generalized Anxiety Disorder

Gwang-Won Kim¹, Moo-Suk Lee², Heoung-Keun Kang³, Tae-Jin Park⁴, Jong-Chul Yang⁵, Gyung-Ho Chung⁶, Gwang-Woo Jeong¹,³

¹Research Institute of Medical Imaging, Chonnam National University Medical School, Gwangju, Korea; ²Psychiatry, Chonnam National University Medical School, Gwangju, Korea; ³Radiology, Chonnam National University Medical School, Gwangju, Korea; ⁴Psychology, Chonnam National University, Gwangju, Korea; ⁵Psychiatry, Chonbuk National University Medical School, jeonju, Korea; ⁶Radiology, Chonbuk National University Medical School, jeonju, Korea

Patients with generalized anxiety disorder (GAD) is associated with abnormalities in the processing and regulation of cognition, and neuropsychological impairment as well. Despite recent studies for identifying the neural circuitry contributing to cognitive control, the differential neural mechanisms for a delayed-response working memory (WM) and cognitive inhibition components in GAD patients have not yet been specified.