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Abstract #3687

Effects of a Nutrient-Combination Diet on Cerebral Blood Flow, Metabolites Levels and Brain Diffusion in ApoE4 and ApoE Knockout Mice

Valerio Zerbi1, 2, Diane Jansen1, Maarten Van Beek1, Roy Haast1, Andor Veltien3, Laus M. Broersen4, Jack JA Van Asten3, Arend Heerschap3, Amanda J. Kiliaan1

1Anatomy, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Netherlands; 2Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, Netherlands; 3Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Netherlands; 4Nutricia Advanced Medical Nutrition, Centre for Specialised Nutrition, Wageningen, Netherlands, Netherlands


Research into Alzheimers disease (AD) suggests that dietary behavior may affect the course of AD. A specific combination of omega-3 fatty acids with precursors and cofactors in membrane synthesis was developed for the dietary management of AD.