Wen Ling1, Francesca
Nicholls1, 2, Silvio Aime3, Daniela Delli
Castelli3, Michel Modo1
1Radiology,
University of Pittsburgh, Pittsburgh, PA, United States; 2dept of
Neuroscience, King's College London, London, United Kingdom; 3Dept
of Chemistry, University of Torino, Torino, Italy
Optimal detection conditions were established for paraCEST to detect different cell populations in vitro. The scanning conditions were further verified by the fact that human neural stem cells can withstand up to 5 hrs without significant effects on their viability. The detection threshold was then evaluated in terms of concentration and voxel size.