Hamed Mojahed1, 2, Fernando Arias-Mendoza2, Truman R. Brown3
1Department of Biomedical Engineering, Columbia University, New York, NY, United States; 2Department of Radiology, Columbia University, New York, NY, United States; 3Department of Radiology and Radiological Science, Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, United States
A new three dimensional zero J-modulation echo planar chemical shift imaging (3D ZJ-EPSI) pulse sequence is implemented on a conventional 3T MR scanner. Water suppressed 1H spectra of the human brain using a CHESS pulse (RF 80&[deg]-80&[deg]-145&[deg]) is acquired using a Sense head coil in quadrature mode. Lipid suppression is achieved using ten saturation bands around the skull. Spatial resolution of 7.57.56 mm3 is achieved in 10:28 min with TR=1500 ms and TE<1 ms. Having an echoless data and zero J-modulation increases the SNR, improves the T2*, and makes it easier to quantify spectra in the fast 3D ZJ-EPSI sequence.