Ladislav Valkovic1, 2, Martin Gajdosik1, Stefan Traussnigg3, Marek Chmelk1, Ivan Frollo2, Michael Trauner3, Siegfried Trattnig1, Martin Krssk1, 3
1MR Centre of Excellence, Department of Radiology, Medical University of Vienna, Vienna, Austria; 2Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia; 3Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
The goal of this study was to test the feasibility of magnetization transfer (MT) for non-invasive distinction of non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH). 31P-MRS MT measurements of ten suspected NAFLD/NASH and of four healthy subjects were performed on 7T system using surface coil (1H/31P). The NASH patients had significantly lower forward rate constants as compared to NAFLD patients and healthy volunteers.