Sabrina Doblas1, Helena S. Leitao1, 2, Philippe Garteiser1, Gaspard d'Assignies1, 3, Feryel Mouri4, Valrie Vilgrain1, 3, Ralph Sinkus1, Carlos F.G.C. Geraldes2, Bernard E. Van Beers1, 3
1U773-CRB3, INSERM, Paris, France; 2Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; 3Radiology Department, Beaujon University Hospital, Clichy, France; 4Hepatology Department, Beaujon University Hospital, Clichy, France
Confounding factors such as steatosis and inflammation can bias the evaluation of hepatic fibrosis by MR elastography or DWI, 2 techniques proposed as non-invasive approaches to the evaluation of chronic liver diseases. Multivariate analysis of MR elastography and DWI data obtained from a cohort of 58 hepatitis patients showed that viscoelastic parameters preferentially responded to fibrosis, whereas the diffusion coefficient was mostly affected by steatosis.