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Abstract #4126

Quantitative Phase Imaging in Mouse Pregnancy

Uday Krishnamurthy1, Yimin Shen2, Gabor Szalai3, Jaladhar Neelavalli2, Bing Wang3, Tinnakorn Chaiworapongsa3, 4, Edgar Hernandez-Andrade3, 4, Nandor Gabor Than3, 4, Ewart Mark Haacke2, Roberto Romero3

1Department of Biomedical Engineering, Wayne State University, Detroit, MI, United States; 2Department of Radiology, Wayne State University, Detroit, MI, United States; 3Perinatology Research Branch, NICHD, NIH, DHHS, Wayne State University, Detroit, MI, United States; 4Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, United States


Using susceptibility weighted imaging (SWI),we have shown that there is significant correlation between venous phase in the umbilical artery and the phase measured from the corresponding lungs and placenta, indicating that phase measurements from the fetal lung or placenta can be used for assessing relative fetal blood oxygenation in mouse pregnancy